Why does calcification (the build up of calcium salts in body tissue) occur and what does it mean? A friend and I both have low grade disease and we have a lot of calcification but we don't understand the significance of this.
This is a very good question and the honest answer is that I don’t know why it happens.
The implications of calification are in terms of response in low grade serous disease. There has only been one small study, which suggested that calcification itself was not associated with better or worse prognosis in low grade serous disease, but more research is needed into this.
We did know that this form of calcification is very typical in low grade serous disease but you do also sometimes see it in high grade serous cancers as well.