I am on chemo (carboplatin and paclitaxel) for a recurrence of ovarian cancer and I am also taking Avastin. I have been experiencing more side effects than before (diarrhoea and joint pain). I will be continuing with Avastin when my chemo ends in about 6 weeks’ time and would like to know if there is evidence or experience out there that the diarrhoea and joint pain will ease when the Avastin is taken without any chemo?
This is a difficult question to answer as both paclitaxel and Avastin can cause diarrhoea and joint pains. They may also make each other work more effectively. There is no specific evidence of the changes in side effects when moving from combination chemotherapy and Avastin to single agent treatment (Avastin on its own). In my experience, however, the symptoms reduce and sometimes disappear.