Pipettes in a lab being used for ovarian cancer research

SIGNPOST: Systematic genetic testing for personalised ovarian cancer therapy

Trial at a glance

Open trial

  • Cancer type: Epithelial – high-grade serous and endometrioid
  • Treatment stage: Other
  • Acronym: SIGNPOST

SIGNPOST: Systematic genetic testing for personalised ovarian cancer therapy

Who can take part

Please note - unless we state otherwise in the summary, you need to talk to your doctor about joining a trial.


You may be able to take part in this clinical trial if you: 

  • have epithelial non-mucinous ovarian cancer, high-grade fallopian tube cancer and primary peritoneal cancer
  • have been offered genetic testing in relation to ovarian cancer 

This is not an exhaustive list. If you're interested in participating in a clinical trial, you should speak to your doctor about what other criteria might apply.

About the trial

Genetic testing in ovarian cancer patients is now being implemented across the NHS.  It's hoped that by doing this, patients across the NHS will have even better treatments and that in some families, cancers will be prevented.

In this study researchers want to find out about:

  • what effect genetic counselling has on a person's emotional wellbeing
  • what gene changes are found in women with ovarian cancer
  • whether those who have gene changes are willing to have screening or treatment to try and prevent ovarian cancer
  • what the costs are for this new genetic testing strategy

There are three parts to this study (you don't have to take part in all aspects of this study):

  • The impact of genetic testing on emotional wellbeing and quality of life.
  • The use of blood and tumour tissue that will include testing for genetic and non­genetic factors that affect ovarian cancer.
  • The storage of blood and/or tumour tissue for future research.

This information was last reviewed on 12/01/2024. Please note that the status of clinical trials can change at short notice. You should always check with your clinical team which trials may be suitable for your situation.